Urivarx - Clinically Proven Bladder Control
What is UriVarx™?
UriVarx™ is a proprietary blend of the following botanical ingredients
- Lindera (Lindera aggregata) extract
- Horsetail (Equistum arvense) extract (aerial parts)
- Cratevox™ Three -leaf caper (Crateva nurvala) extract (bark)
Additional ingredients are vegetable capsule (HPMC, water), rice flour and silica.
Linder extract (Lindera aggregate) is a root that has been used to support healthy urinary and kidney function.*
Horsetail extract (Equisetum arvense) is a plant listed on the German Commission E monograph to support and maintain the health of the urinary tract. *
Cratevox™ Three -leaf caper extract (Crateva nurvala) bark demonstrated in pre-clinical studies to enhance bladder tone. In an uncontrolled clinical study, Crateva nurvala bark supported healthy urinary function and bladder tone after 3 months of use.*
Patented UriVarx™ specifically targets the bladder and surrounding tissues to promote normal urination and strong bladder tone. UriVarx™ is clinically proven in an 8-week double blind placebo controlled clinical trial in 150 patients to support bladder tone and function.
Drug therapy indicated for bladder control works via an anticholinergic action and has side effects such as dry mouth, dry eyes, blurred vision and memory loss. UriVarx™ is a dietary supplement to support healthy bladder function and does not have an anticholinergic effect or produce these side effects.
Bladder Functions And Conditions
The bladder is a hollow muscular organ shaped like a balloon. It sits in your pelvis and is held in place by ligaments attached to other organs and the pelvic bones. The bladder stores urine until you are ready to go to the bathroom to empty it. It swells into a round shape when it is full and gets smaller when empty. If the urinary system is healthy, the bladder can hold up to 16 ounces (2 cups) of urine comfortably for 2 to 5 hours.
Circular muscles called sphincters help keep urine from leaking. The sphincter muscles close tightly like a rubber band around the opening of the bladder into the urethra, the tube that allows urine to pass outside the body.
Nerves in the bladder tell you when it is time to urinate, or empty your bladder. As the bladder first fills with urine, you may notice a feeling that you need to urinate. The sensation to urinate becomes stronger as the bladder continues to fill and reaches its limit. At that point, nerves from the bladder send a message to the brain that the bladder is full, and your urge to empty your bladder intensifies. When you urinate, the brain signals the bladder muscles to tighten, squeezing urine out of the bladder. At the same time, the brain signals the sphincter muscles to relax. As these muscles relax, urine exits the bladder through the urethra. When all the signals occur in the correct order, normal urination occurs.
What causes problems in the urinary system?
Problems in the urinary system can be caused by aging, illness, or injury. As you get older, changes in the kidneys’ structure cause them to lose some of their ability to remove wastes from the blood. Also, the muscles in your ureters, bladder, and urethra tend to lose some of their strength. You may have more urinary infections because the bladder muscles do not tighten enough to empty your bladder completely. A decrease in strength of muscles of the sphincters and the pelvis can also cause incontinence, the unwanted leakage of urine. Illness or injury can also prevent the kidneys from filtering the blood completely or block the passage of urine.
UriVarx™ was evaluated in two clinical studies. The first study compared the efficacy of crateva, horsetail and mineral combination compared to UriVarx™. Comparison was made using the percent (%) reduction in frequency and urination and nocturia for each of the treatment groups at months one and three. Following one month of use, UriVarx™ was more effective in reducing the frequency of day urination (Figure 1) and superior in reducing nocturnia (Figure 2) compared to crateva and horsetail alone.
UriVarx™ was evaluated in an 8-week, double-blind, randomized, placebo-controlled, clinical study conducted at two sites. UriVarx™ was assessed in 142 subjects (81 female and 61 male) on urinary frequency and urgency. Data was collected at 2, 4, and 8 weeks. The primary outcome measure was self-reported urinary frequency defined as the number of voluntary diurnal and/ or nocturnal micturitions. Baseline reported measurements were similar between groups. At week 8, mean (n/day) urinary day frequency was significantly lower in subjects administered UriVarx™ compared to placebo (Figure 3). Similarly, mean episodes of nocturia and urgency were significantly fewer versus placebo (Figures 4 & 5). Significant improvements in quality of life were reported at end of study in comparison to placebo.*
There were no adverse events leading to discontinuation. Five episodes of transient adverse reactions were reported in the UriVarx™ group which included diarrhea (2.9%), UTI (2.9%) and flatulence (1.5%).
Q: My order is incomplete. What should I do?
A: For any orders that don’t complete or issue an error message, contact Customer Service at 1.800.748.6119, from 8:00 a.m. – 5:00 p.m. PST, Monday through Friday to confirm your order and your payment information.
Q: When will my order ship?
A: Orders received before 1:00 p.m. PST will ship the same day. Orders received after 1:00 p.m. PST will be shipped the following business day (excluding holidays).
Q: How long will it take for my order to get here?
A: All orders are shipped via USPS, and are expected to arrive in two to five business days from the ship date within the 48 continental states.
Q: How much is shipping?
A: Shipping cost $8.95 for single bottle orders. Shipping is free with multiple bottle orders within USA. Additional charges apply for expedited shipping and international orders.
Q: Do you ship to international addresses?
A: Yes, UriVarx is available worldwide. All prices are in USD. Additional shipping and handling fees will be added to international orders. You can contact us prior to ordering to get an estimate on shipping.
Q: I didn’t receive my order. What should I do?
A: Contact us within 15 days of your order date so we will be able to track or replace your order.
Q: Do you offer any kind of guarantee?
A: Yes. We support our product 100%. If you are not satisfied with UriVarx, call 1.800.748.6119. You will receive return information that must be completed within 30 days of the original order shipment for a full refund. If more than one bottle was purchased, additional bottles must be returned unopened.
Q: How do I make a return?
A: Any claim for credit or return goods request must be made within thirty (30) days of receipt and require a return merchandise authorization (RMA) number. Please email us at UriVarxCustomerService@innovuspharma.com, or call Customer Service at 1.800.748.6119, from 8:00 a.m. – 5:00 p.m. EST, Monday through Friday, to receive a RMA number. Upon receipt of authorized returned products, a refund for the original purchase price less the original shipping and handling charge ("Partial refund") will be issued. To obtain a partial refund, products must be returned within thirty (30) days of receiving an RMA number.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
In clinical trials, UriVarx™ has been used safely with minor side effects for up to 8 weeks. There were no adverse events leading to discontinuation. Five episodes of transient adverse reactions were reported in the UriVarx™ group which included diarrhea (2.9%), UTI (2.9%) and flatulence (1.5%). Pregnant women and women who are nursing should not take supplements without first talking to their doctor.